Quanah is located in Hardeman County. Southeast of Quanah is the ghost town of Medicine Mound, which consists of two buildings. Quanah is also home to a branch of the Helen J. Farabee Mental Health Centers. Natural disasters like flood and fire have struck the city on numerous occasions. However, the city’s economic position as a shipping center for cotton, barley, wheat, oats, and cattle was improved with the discovery of the Conley oilfield.